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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TXNRD2
All Species:
22.42
Human Site:
T301
Identified Species:
32.89
UniProt:
Q9NNW7
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NNW7
NP_006431.2
524
56507
T301
V
T
W
E
D
S
T
T
G
K
E
D
T
G
T
Chimpanzee
Pan troglodytes
XP_001166615
481
51948
G271
I
E
H
M
A
S
H
G
T
R
F
L
R
G
C
Rhesus Macaque
Macaca mulatta
NP_001152971
524
56314
T301
V
T
W
E
D
C
T
T
G
K
E
D
T
G
T
Dog
Lupus familis
XP_850181
509
55065
S288
V
T
W
E
N
L
T
S
G
K
E
D
V
G
T
Cat
Felis silvestris
Mouse
Mus musculus
Q9JLT4
524
56434
S301
V
T
W
E
D
H
A
S
G
K
E
D
T
G
T
Rat
Rattus norvegicus
Q9Z0J5
526
56406
S303
V
T
W
E
D
L
A
S
G
K
E
D
V
G
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001116163
518
56137
L295
V
T
W
K
N
T
E
L
G
T
E
E
T
D
S
Frog
Xenopus laevis
NP_001080052
504
54666
S281
V
T
W
K
N
T
Q
S
G
K
E
G
V
D
I
Zebra Danio
Brachydanio rerio
NP_898895
602
65949
S376
R
I
K
V
T
A
K
S
T
E
S
E
E
V
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P91938
596
64304
T375
V
K
Y
K
N
V
E
T
G
E
E
A
E
D
V
Honey Bee
Apis mellifera
NP_001171496
537
59227
R316
V
H
W
V
D
K
D
R
Q
T
H
Q
D
T
F
Nematode Worm
Caenorhab. elegans
Q17745
667
74094
W434
A
G
K
Y
R
V
F
W
P
K
K
N
E
E
T
Sea Urchin
Strong. purpuratus
XP_797733
490
53044
G272
V
R
W
R
S
D
Q
G
Q
E
G
H
G
E
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P48641
499
53852
V279
K
T
D
Q
G
I
K
V
I
S
S
H
G
E
E
Baker's Yeast
Sacchar. cerevisiae
P41921
483
53422
I261
N
V
H
K
L
S
K
I
V
K
V
E
K
N
V
Red Bread Mold
Neurospora crassa
Q873E8
468
50294
E260
A
I
N
F
K
E
G
E
G
E
Q
S
I
S
D
Conservation
Percent
Protein Identity:
100
91
98.2
83.2
N.A.
84.5
82.6
N.A.
N.A.
72.9
68.6
47
N.A.
48.9
53
40.7
55.7
Protein Similarity:
100
91.2
99
91.4
N.A.
91.5
90.8
N.A.
N.A.
86
82.2
62.2
N.A.
62.4
68.5
56.2
69.8
P-Site Identity:
100
13.3
93.3
73.3
N.A.
80
73.3
N.A.
N.A.
40
40
0
N.A.
26.6
20
13.3
13.3
P-Site Similarity:
100
26.6
93.3
86.6
N.A.
86.6
80
N.A.
N.A.
73.3
66.6
26.6
N.A.
53.3
20
26.6
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
33.7
32.8
34.7
Protein Similarity:
N.A.
N.A.
N.A.
51.7
53
52.4
P-Site Identity:
N.A.
N.A.
N.A.
6.6
13.3
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
26.6
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
13
0
0
0
7
7
13
0
0
0
0
7
0
0
0
% A
% Cys:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
7
% C
% Asp:
0
0
7
0
32
7
7
0
0
0
0
32
7
19
7
% D
% Glu:
0
7
0
32
0
7
13
7
0
25
50
19
19
19
7
% E
% Phe:
0
0
0
7
0
0
7
0
0
0
7
0
0
0
19
% F
% Gly:
0
7
0
0
7
0
7
13
57
0
7
7
13
38
0
% G
% His:
0
7
13
0
0
7
7
0
0
0
7
13
0
0
0
% H
% Ile:
7
13
0
0
0
7
0
7
7
0
0
0
7
0
7
% I
% Lys:
7
7
13
25
7
7
19
0
0
50
7
0
7
0
0
% K
% Leu:
0
0
0
0
7
13
0
7
0
0
0
7
0
0
0
% L
% Met:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
7
0
7
0
25
0
0
0
0
0
0
7
0
7
0
% N
% Pro:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% P
% Gln:
0
0
0
7
0
0
13
0
13
0
7
7
0
0
0
% Q
% Arg:
7
7
0
7
7
0
0
7
0
7
0
0
7
0
0
% R
% Ser:
0
0
0
0
7
19
0
32
0
7
13
7
0
7
7
% S
% Thr:
0
50
0
0
7
13
19
19
13
13
0
0
25
7
38
% T
% Val:
63
7
0
13
0
13
0
7
7
0
7
0
19
7
13
% V
% Trp:
0
0
57
0
0
0
0
7
0
0
0
0
0
0
0
% W
% Tyr:
0
0
7
7
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _